The answer is the "gold standard" double blind, placebo controlled study.

答案是“金标准”，双盲，安慰剂对照研究。

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DESIGN: a randomized grouping comparison and placebo controlled study.

设计：随机对比观察，安慰剂对照。

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The study was a double blind placebo controlled study adequately powered for OS as primary end-point.

这项研究是一项双盲，安慰剂对照的研究，以OS作为主要终止点。

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Packer says this is the first placebo-controlled study in acute heart failure to show a clinical benefit.

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This study is actually the first of four placebo-controlled, Phase III trials to be completed.

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Claire Bombardier, the University of Toronto researcher who had conducted Merck's big ulcer study, criticized the new studies for not being placebo-controlled.

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